Letters written by Julia Rush, wife of Benjamin Rush, mainly to her husband, with one to Samuel Stockton and one to Mary Rush. Eight letters were written during the 1793 yellow fever epidemic. The letters are not included in Lyman Butterfield's edition of Benjamin Rush's letters, vol. 30 of APS Memoirs (1951).

This volume includes several printed and manuscript items related to the death of Caspar Wistar, in January 1818.

Sarah Franklin Bache (1743-1808), a Revolutionary War patriot and daughter of Benjamin Franklin, led an active public life according to the standards of womanhood in the late eighteenth century. As the daughter of Benjamin Franklin she had an unusual access, for a woman, to the political life in revolutionary Philadelphia. Although her primary role was of caretaker of her family and home, Bache played an active role in the Revolution through her relief work and as her father's political hostess. The Sarah Franklin Bache papers consist of incoming and outgoing correspondence ranging from 1768 to 1807 mostly of a personal nature to and from friends and relatives. The correspondence of her relatives includes her nephew William Temple Franklin, her brother William Franklin and her children.

This autobiography relates Rush's experiences in college and medical school; his meetings with notable doctors; his life in Scotland, England, and France; his medical views; the military and politics during the Revolutionary War; and brief sketches of personalities of that period.

Jacob Hiltzheimer, farmer and assemblyman, emigrated from Germany to Philadelphia in 1748 and lead a moderately active political and social life. He was a successful farmer and raised select livestock in the city of Philadelphia. He also boarded horses including those of John Penn and George Washington. He served in the Pennsylvania Assembly for 11 consecutive years beginning in 1786. He was an active contributor in civil affairs and took a remarkable enthusiastic interest in events, in persons, and in every day life all of which he wrote down in his diary. As a result of his Revolutionary War and political acquaintances his contacts were numerous. Hiltzheimer's record of social affairs are for the most part routine daily events such as buying and trading horses, attending barbecues and funerals, and drinking punch. However it is his every day accounts that also records significant events such as the Revolutionary War, transactions of the Pennsylvania Assembly, and Philadelphia's yellow fever epidemics, as well as the dealings of significant people including George Washington, Thomas Mifflin, and John Hancock.

This item contains entries about prominent people (primarily accounts of their deaths); Philadelphia events and gossip; the Pennsylvania Hospital; questions for Meriwether Lewis on Indian physical history, medicine, morals, and religion; and his views on marriage, religion, physicians, etc. Also includes meeting with Captain Wells and Little Turtle; speculations on Indian skin color at the equator.

This volume contains medical notes by Wistar, including observations on yellow fever and arguments to prove its foreign origin, facts relative to the progress of the fever in 1797, the infection and death of Colonel Van Emburgh, the infection of the crew of the ship "Deborah" and of the Durham boat (1802), an account of the diseases which afflicted the family of James Hammar in Montgomery County (Pa.), facts relating to the typhus fever of 1812-1813, case histories (1796-1803), temperature chart (1758-1759, 1760), and a thermometrical journal (1760-1765) kept by Charles Norris and copied by Wistar from notes in possession of Joseph Parker Norris.

The collection includes letters between Hutchinson and his uncle Israel Pemberton, written while Hutchinson was a student of medicine in London. There are also 12 tickets of admission to medical lectures in Philadelphia and London, including one given by William Hunter, and 3 unused cards of admission to Hutchinson's own lectures. Miscellaneous items include Hutchinson's marriage certificate; genealogical data on the Hutchinson, Hare, and Pemberton families; and stock certificates, 1857-1872, of the McKean and Elk Land and Improvement Company. Materials dated post-1793 are to and from Hutchinson family members.